Indicators on Genetic methylation testing You Should Know
inside the human genome, 5mC is routinely located in CpG dinucleotides, with these internet sites staying hotspots for mutations including in tumor suppressor genes. for instance, CpG island (CGI) mutations in the coding area of p53, a gene involved in genome stabilization and mobile cycle/apoptotic responses, add to ~25% of its inactivating mutati